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BUN/CREATININE RATIO

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BUN/CREATININE RATIO

Product Details

Clinical Significance

The BUN/Creatinine ratio is useful in the differential diagnosis of acute or chronic renal disease. Reduced renal perfusion, e.g., congestive heart failure, or recent onset of urinary tract obstruction will result in an increase in BUN/Creatinine ratio. Increased urea formation also results in an increase in the ratio, e.g., gastrointestinal bleeding, trauma, etc. When there is decreased formation of urea as seen in liver disease, there is a decrease in the BUN/Creatinine ratio. In most cases of chronic renal disease the ratio remains relatively normal.

Alternative Name(s)

BUN, Blood Urea Nitrogen

Reference Range(s)

Bun/Creatinine Ratio	6-22 (calc)
Urea Nitrogen (BUN)
Age	Male (mg/dL)	Female (mg/dL)
<1 Month	4-12	3-17
1-11 Months	2-13	4-14
1-3 Years	3-12	3-14
4-19 Years	7-20	7-20
≥20 Years	7-25	7-25

Creatinine
Age	Male (mg/dL)	Female (mg/dL)

18-19 years	0.60-1.26	0.50-1.00
20-49 years	0.60-1.35	0.50-1.10
50-59 years	0.70-1.33	0.50-1.05
60-69 years	0.70-1.25	0.50-0.99
70-79 years	0.70-1.18	0.60-0.93
≥80 years	0.70-1.11	0.60-0.88

For patients >49 years of age, the upper reference limit for creatinine is approximately 13% higher for people identified as African-American.

eGFR Non-African American	≥60 mL/min/1.73m2
eGFR African American	≥60 mL/min/1.73m2

Test Prep: None Indicated